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Venu Thottempudi (Telugu: వేణు తొట్టెంపూడి) (born 4 June 1976) is an Indian actor who primarily works in Telugu Cinema. He has acted in several successful Telugu movies as a lead actor. He is the nephew of Telugu film director B. Gopal.

After finishing his engineering from Dharwad Engineering College, Venu started pursuing acting as his career. For his first acting job, he was cast as the main lead in a movie directed by P. Bharathiraja. After a brief period of shooting, the movie was stalled and later cancelled due to production problems. After this, Venu's friends namely Shyamprasad, Sai and Prabhu helped him become an actor. To promote Venu, Venkata Shyamprasad formed S. P. Entertainments banner and the other two friends were involved in design and planning. Under this banner, in 1999 Venu started his career with the movie Swayamvaram, directed by K. Vijaya Bhaskar. Co-starring Laya, the movie was very successful at box-office and Venu bagged a Nandi Special Jury Award for the movie. Venu became well known for his dialogue delivery, timing, expressions and clear portray of emotions. In 2000, Venu won the boxoffice once again with Chiru Navvuto. G.Ramprasad, who earlier worked with B.Gopal as an assistant director is roped in as the director for this movie. This movie co-starring Shaheen Khan was produced once again by S.P.Entertainments. Chiru Navvuto became one of the milestones in Venu's career.

Having two good hits in the early stages of his career, Venu landed up with a bunch of offers. Later he appeared in a few unsuccessful films like Manasu Paddanu Kaani directed by Veeru and Veedekkadi Mogudandi? directed by E. V. V. Satyanarayana. He later bounced back with couple of hits like Hanuman Junction directed by M. Raja and Pellam Oorelithe directed by S. V. Krishna Reddy. In 2003, his movie Kalyana Ramudu, co-starring Prabhu Deva and Nikita Thukral, was directed by G. Ram Prasad. His next releases were Sadaa Mee Sevalo(2005) directed by Neelakanta, Bahumati directed by S. V. Krishna Reddy and Allare Allari directed by Muppalaneni Siva.

In 2007, his movie Yamagola Malli Modalayindi co-starring Srikanth, Meera Jasmine and Reemma Sen was released. This movie was successful at the box-office. In 2008, he was seen in a small yet vital role in the movie Chintakayala Ravi starring Venkatesh. In 2009 he was seen in Gopi Gopika Godavari directed by Vamsy and co-starring Kamalinee Mukherjee. In 2011, Venu was seen in Dileep Polan's Mayagadu opposite Charmy Kaur. His next release is titled Ramachari, directed by Eshawar. He is paired with Kamalinee Mukherjee in this movie. Soundtrack of the movie was released in October 2011. Venu was also seen in N. T. Rama Rao Jr.'s movie Dammu, directed by Boyapati Srinu